High Sensitivity Micro-Elastometry: Applications in Blood Coagulopathy
نویسندگان
چکیده
منابع مشابه
A portable blood plasma clot micro-elastometry device based on resonant acoustic spectroscopy.
Abnormal blood clot stiffness is an important indicator of coagulation disorders arising from a variety of cardiovascular diseases and drug treatments. Here, we present a portable instrument for elastometry of microliter volume blood samples based upon the principle of resonant acoustic spectroscopy, where a sample of well-defined dimensions exhibits a fundamental longitudinal resonance mode pr...
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Trauma is a serious global health problem, accounting for approximately one in 10 deaths worldwide. Uncontrollable bleeding accounts for 39% of trauma-related deaths and is the leading cause of potentially preventable death in patients with major trauma. While bleeding from vascular injury can usually be repaired surgically, coagulopathy-related bleeding is often more difficult to manage and ma...
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PURPOSE To characterize the imaging features of intracerebral hemorrhages in coagulopathies that alter prothrombin time or partial thromboplastin time. METHODS A fluid-blood level was defined as a horizontal interface between hypodense bloody serum layered above hyperdense settled blood. The prevalence of fluid-blood levels in acute intracerebral hemorrhages was determined on third-generation...
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as the millisecond increase in cycle length per mm Hg rise in systolic pressure. The slope is an index of baroreflex sensitivity and was found to have an average value of 12.8 in 18 subjects without hypertension and 2.8 in 12 others with hypertension. When all results were pooled, there was an inverse relationship between the resting mean arterial pressure and slope of the baroreflex regression...
متن کاملHigh sensitivity PCR assay in plastic micro reactors.
Small volume operation and rapid thermal cycling have been subjects of numerous reports in micro reactor chip development. Sensitivity aspects of the micro PCR reactor have not been studied in detail, however, despite the fact that detection of rare targets or trace genomic material from clinical and/or environmental samples has been a great challenge for microfluidic devices. In this study, a ...
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ژورنال
عنوان ژورنال: Annals of Biomedical Engineering
سال: 2013
ISSN: 0090-6964,1573-9686
DOI: 10.1007/s10439-013-0817-3